Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Neuroscience

    An acute microglial metabolic response controls metabolism and improves memory

    Anne Drougard, Eric H Ma ... J. Andrew Pospisilik
    1. Cell Biology

    Eugenol mimics exercise to promote skeletal muscle fiber remodeling and myokine IL-15 expression by activating TRPV1 channel

    Tengteng Huang, Xiaoling Chen ... Zhiqing Huang
    Eugenol has the potential as a novel exercise mimetic, and TRPV1 may represent a promising target for the development of exercise mimetics.
    1. Cell Biology

    The non-mitotic role of HMMR in regulating the localization of TPX2 and the dynamics of microtubules in neurons

    Yi-Ju Chen, Shun-Cheng Tseng ... Eric Hwang
    The protein hyaluronan-mediated motility receptor interacts with microtubules to enhance their stability and recruits TPX2 to promote microtubule emanation in neurons.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Identification of a third myosin-5a-melanophilin interaction that mediates the association of myosin-5a with melanosomes

    Jiabin Pan, Rui Zhou ... Xiang-dong Li
    In addition to the exon-F-binding domain and the globular tail domain-binding motif, the actin-binding domain of melanophilin interacts with myosin-5a tail region and mediates the association of myosin-5a with melanosomes.
    1. Cell Biology

    Metabolic regulation of misfolded protein import into mitochondria

    Yuhao Wang, Linhao Ruan ... Rong Li
    The conserved AMP-activated protein kinase inhibits mitochondrial import of misfolded proteins and helps preserve mitochondrial and cellular fitness under proteotoxic stress.
    1. Cell Biology

    Novel autophagy inducers by accelerating lysosomal clustering against Parkinson's disease

    Yuki Date, Yukiko Sasazawa ... Shinji Saiki
    1. Cell Biology

    Statin-mediated reduction in mitochondrial cholesterol primes an anti-inflammatory response in macrophages by upregulating Jmjd3

    Zeina Salloum, Kristin Dauner ... Xiaohui Zha
    Genetic and biochemical analysis reveals that the anti-inflammatory effect of statins is due to decreasing cholesterol in macrophages and upregulating Jmjd3 to achieve the anti-inflammatory action.

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  3. Silke Hauf
    Virginia Tech, United States
  4. See more editors