I am also having this same issue. I notice I need to re-select the "Accept Routes" toggle as enabled every time my computer resumes from sleep.

I think the Tailscale GUI Tray is not properly remembering the past toggle setting.

Similar issue here with ubuntu 22.04.4 LTS and tailscale 1.64.0

With tailscale already connected, post-boot and login to machine:
Toggling "Accept routes" on and off in the UI has no effect.
Issuing "tailscale up --accept-routes=true" from the command line adds routes as expected.
Subsequently toggling "accept routes" in the UI adds and removes the routes as expected.

Log out of tailscale and back in again, with "Accept routes checked", routes are not added.
Toggle "accept routes" in UI has no effect.
Issuing "tailscale up --accept-routes=true" from the command line adds routes as expected.
Subsequently toggling "accept routes" in the UI adds and removes the routes as expected.

It seems that telling tailscale to accept routes from the command line is key, but that this is not preserved between tailscale login sessions.

Wonder if it's because of this?

$ tailscale up --accept-routes=true
Error: changing settings via 'tailscale up' requires mentioning all
non-default flags. To proceed, either re-run your command with --reset or
use the command below to explicitly mention the current value of
all non-default settings:

	tailscale up --accept-routes --shields-up

May need to be smarter in the way the tailscale up commands are built. That appears to be the command run when that toggle is enabled. Ran it manually and got that. Ran the command with the --shields-up option and it works.