3,242 results found
    1. Computational and Systems Biology
    2. Neuroscience

    On the objectivity, reliability, and validity of deep learning enabled bioimage analyses

    Dennis Segebarth, Matthias Griebel ... Robert Blum
    A comparison of different bioimage analysis pipelines reveals how deep learning can be used for automatized and reliable analysis of fluorescent features in biological datasets.
    1. Neuroscience

    Large-scale electrophysiology and deep learning reveal distorted neural signal dynamics after hearing loss

    Shievanie Sabesan, Andreas Fragner ... Nicholas A Lesica
    Deep neural network modeling of auditory processing identifies distorted cross-frequency interactions as the key problem for the processing of speech in noise after hearing loss.
    1. Neuroscience
    2. Physics of Living Systems

    Revealing architectural order with quantitative label-free imaging and deep learning

    Syuan-Ming Guo, Li-Hao Yeh ... Shalin B Mehta
    Advances in quantitative phase and polarized light microscopy, combined with deep learning, reveal the architecture of human brain tissue.
    1. Cell Biology
    2. Immunology and Inflammation

    Deep-learning-based three-dimensional label-free tracking and analysis of immunological synapses of CAR-T cells

    Moosung Lee, Young-Ho Lee ... YongKeun Park
    Rapid, label-free, volumetric, and automated assessment of the immunological synapse dynamics is demonstrated by combining optical diffraction tomography and deep-learning-based segmentation, providing a new option for immunological research.
    1. Stem Cells and Regenerative Medicine

    Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes

    Francis Grafton, Jaclyn Ho ... Mohammad Ali Mandegar
    Deep learning combined with induced pluripotent stem cell technology is an effective method to interrogate cellular phenotypes and predict patterns of cardiotoxicity in vitro.
    1. Computational and Systems Biology
    2. Neuroscience

    Towards deep learning with segregated dendrites

    Jordan Guerguiev, Timothy P Lillicrap, Blake A Richards
    A multi-compartment spiking neural network model demonstrates that biologically feasible deep learning can be achieved if sensory inputs and higher-order feedback are received by different dendritic compartments.
    1. Neuroscience

    Scratch-AID, a deep learning-based system for automatic detection of mouse scratching behavior with high accuracy

    Huasheng Yu, Jingwei Xiong ... Wenqin Luo
    Scratch-AID, a deep learning-based system for automatic quantification of mouse scratching behavior, could replace labor-intensive manual quantification and facilitate high through-put anti-itch drug screening.
    1. Computational and Systems Biology

    Genome-scale annotation of protein binding sites via language model and geometric deep learning

    Qianmu Yuan, Chong Tian, Yuedong Yang
    Integration of language model and geometric deep learning enables accurate and efficient genome-scale annotation of comprehensive protein-ligand binding sites.
    1. Computational and Systems Biology
    2. Ecology

    Collaborative hunting in artificial agents with deep reinforcement learning

    Kazushi Tsutsui, Ryoya Tanaka ... Keisuke Fujii
    Collaborative hunting, characterized by the division of roles among predators, has emerged within a group of artificial agents through deep reinforcement learning.
    1. Developmental Biology

    Tracking cell lineages in 3D by incremental deep learning

    Ko Sugawara, Çağrı Çevrim, Michalis Averof
    Incremental deep learning enables accurate tracking of cell lineages in 3D with a modest investment in time and effort.

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