Extended Data Table 4 Potential use of the AI system in two clinical applications

From: International evaluation of an AI system for breast cancer screening

  1. a, Simulation, using the UK test set, in which the AI system is used in place of the second reader when it concurs with the first reader. In cases of disagreement (12.02%) the consensus opinion was invoked. The high performance of this combination of human and machine suggests that approximately 88% of the effort of the second reader can be eliminated while maintaining the standard of care that is produced by double reading. The decision of the AI system was generated using the first reader operating point (i) shown in Fig. 2a. Confidence intervals are Wald intervals computed with the Obuchowski correction for clustered data. b, Evaluation of the AI system for low-latency triage. Operating points were set to perform with high NPV and PPV for detecting cancer in 12 months.
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