The Lancet

Among 20 leading risk factors for years of life lost in 2040, reference forecasts point to three metabolic risks—high blood pressure, high BMI, and high fasting plasma glucose—as top risk variables. Building on these and other risk factors, the concept of metabolic health is attracting a lot of attention among the scientific community. Find out more in a Lancet Diabetes & Endocrinology Review: hubs.li/Q02xhY8Q0 👇 Metabolic health and selected data-driven cluster approaches for cardiometabolic risk stratification

We are thrilled to announce a groundbreaking partnership between JACC and The Lancet This collaboration leverages our collective strengths to enhance the quality, reach, and impact of cardiovascular research globally. Join us as we advance clinical care and public policy, improving outcomes and shaping the future of health care. Discover more about our initiatives and how we're setting new standards in academic publishing: https://bit.ly/3WAncZE #JACC

Our homes and our health are inextricably linked – this fact isn’t new. In 1922, The Lancet published a letter stating: “One might have imagined that science and common sense would by now have appreciated the importance of such considerations.” And yet a century on, more than 1 billion people lived in urban slums or slum-like conditions in 2022, with this figure expected to triple by 2050, according to estimates by the UN Statistics Division. A new Lancet Editorial examine housing as an overlooked social determinant of health; “Making housing a priority public health intervention not only presents a pivotal opportunity, but a moral imperative.” Find out more ▶️ https://hubs.li/Q02v_P0-0

🆕 “Global study reveals stark differences between females and males in major causes of disease burden, underscoring the need for gender-responsive approaches to health” https://hubs.li/Q02v_BJR0 👇 Figure: Global rankings of the top 20 causes of DALYs globally for females and males, age-standardised (10 years and older), 2021

The prevalence of #ParkinsonsDisease is the fastest growing among neurodegenerative disorders. Due to longer life expectancies and a higher proportion of elderly people, prevalence of the disease will continue to rise unless prevention strategies are found. Join our upcoming Lancet Webinar and hear from a panel of experts as they explore advances in Parkinson’s disease genetics and how these have influenced clinical practice and can contribute to new diagnostic criteria. Register now: https://hubs.li/Q02v_L_X0 🗓️ May 22, 2024 🕘 09:00 GMT / 10:00 CEST

“5 years ago, the field of digital health was overhyped with little substance.” So say editors of The Lancet Digital Health, which has just entered its fifth year 🎉 “When we launched the journal in May, 2019, we were ambitious, yet cautious. We aimed to amplify rigorous research exploring the potential of digital health, and openly acknowledged and critiqued the difficulties of this rapidly advancing field.” With AI and large language models a hot topic across sectors, the journal’s anniversary Editorial explores the past, present, and potentials of digital health in medicine. Read ▶️ https://hubs.li/Q02vhzbp0 #DigitalHealth

An “impending calamity” that lacks resonance and action. This is how authors of a new report have described the antimicrobial resistance (AMR) issue. 📄 Two years ago, The Lancet published a study estimating AMR was directly responsible for 1.27 million deaths in 2019, mostly in low- and middle-income countries. While dozens of countries around the world have established national plans on AMR, funds and action are lacking. “AMR is not yet a subject that resonates with the average member of the public and this, in turn, influences how much time politicians are willing to invest in the issue”, says Scott Weeze, Professor at the University of Guelph and member of the Global Leaders Group (GLG) on Antimicrobial Resistance. 🗣️ Some fault communication. “The language we are using is not connecting with people”, argues Professor Otto Cars, Uppsala University, Sweden. He continues: “Instead of focusing on terms like ‘AMR’ or the names of bacteria and antibiotics, we should be talking about the diseases that are going to become untreatable—most people know what pneumonia is.” With concerning projections—by 2035, the cost to health care of treating antibiotic-resistant infections could reach US$412 billion per year—motivating public and political engagement is paramount. There are hopes that the new report and September’s second UN General Assembly high-level meeting on AMR will do just that. Read more from Talha Burki ▶️ https://hubs.li/Q02v14rb0 Image credit: putilich from Getty Images via Canva

Misinformation is not a new phenomenon – far from it. However, the COVID-19 pandemic highlighted how infodemics (an overabundance of information, including mis- and disinformation) pose a threat to health and confidence in research. Two new papers—one in The Lancet Public Health, the other in The Lancet Infectious Diseases—hone in on: 1️⃣ Addressing infodemics through the preventive lens of public health 2️⃣ The social histories of misinformation and infodemics across four pandemic case studies “The spread of health misinformation has always been a public health challenge that has necessitated innovative solutions from medical and public health communities”, write Sabrina L Jin and colleagues. Find links to both papers in the comments section👇 Figure: Public health prevention framework for managing information ecosystems

Many people with breast cancer are being ‘systematically left behind’ due to inaction on inequities and hidden suffering, says a new Lancet Commission. Explore authors’ recommendations to address these urgent challenges in #BreastCancer ▶️ https://hubs.li/Q02sWLSz0

In recent decades, advances in breast cancer research and treatment have led to a 40% fall in breast cancer deaths in some high-income countries. However, the burden of breast cancer still looms large worldwide. Join us tomorrow as we launch a new Lancet Commission, with recommendations to address key challenges in breast cancer. Register now ⬇ bit.ly/3x2EDaE