Table 1 Summary of data used in large-scale quantitative study

Dataset	Organ site(s)	Categories assessed	Number of slides in the database	Number of patches in the database	Number of slides in the query set	Number of patches in the query set
Organ-specific	Prostate	9 histologic features	15	45,000 (5,000 per feature)	5	9,000 (1000 per feature)
Multi-organ	Prostate, breast, colon	10 histologic features	45	87,000 (3,000 per feature/organ^a)	15	14,500 (500 per feature/organ^a)
Gleason grading^b	Prostate	Non-tumor and Gleason Patterns 3,4,5 (NT, GP3, GP4, GP5)	20	40,000 (10,000 in each category)	5	8,000 (2,000 in each category)

To avoid biases in the evaluation, we randomly subsampled the original annotated regions, resulting in 5,000 patches per histologic feature per organ
^aIn our study, no lymphocytes were found upon non-exhaustive review of the prostate specimens, so the number of patches exclude this
^bNot every patch in this dataset was concurrently labeled with histologic features, so 4,000 database patches and 1,600 query patches with both types of annotations were used for assessing the simultaneous match of both Gleason pattern and histologic feature

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