Table 3 Prognostic performance of direct risk prediction using histologic scoring provided by DLS and pathologists.

From: Deep learning models for histologic grading of breast cancer and association with disease prognosis

Scoring method

C-index (All cases; n = 829)

DLS

Pathologist

Combined Histologic Grade [1,2,3]

0.60 [0.55, 0.65]

0.58 [0.51, 0.63]

Summed Score Discrete [3,4,5,6,7,8,9]

0.59* [0.53, 0.64]

0.58* [0.51, 0.63]

Summed Score Continuous [3.00–9.00]

0.58* [0.52, 0.64]

N/A

  1. DLS deep learning system.
  2. *Planned non-inferiority test comparing these configurations: DLS Summed Score Continous and Pathologist Summed Score Discrete.
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