Fraser Kelton’s Post

Generative A.I. Arrives in the Gene Editing World of CRISPR:Now, new A.I. technology is generating blueprints for microscopic biological mechanisms that can edit your DNA, pointing to a future when scientists can battle illness and diseases with even greater precision and speed than they can today.

Generative A.I. Arrives in the Gene Editing World of CRISPR Much as ChatGPT generates poetry, a new A.I. system devises blueprints for microscopic mechanisms that can edit your DNA https://lnkd.in/dTtG2BgR

Generative AI for gene editing #artificialintelligence #AI

Decoding Genes and Cells with GenePT: A Simple Yet Powerful Foundation Model Leveraging ChatGPT The NCBI is a useful tool for learning about genetic and cellular functions, thanks to the development of GenePT, a straightforward but efficient method that represents genes and cells using GPT-3.5. This method works well for identifying gene functionality groups and predicting interactions between genes, among other applications. However, because the existing GenePT system relies solely on publicly available gene summaries and descriptions, it might miss some lesser-known features that aren’t listed in databases like NCBI. Applications of GenePT -Capture Gene functionality -Do Accurate predictions in chromatin dynamics and dosage sensitivity -GenePT cell embeddings capture biological variations further readings: https://lnkd.in/e68TmHrZ #personalizedmedicine #precisionmedicine #ai #chatgpt

I define life as an entity that can harvest energy from its environment and replicate its patterns of coherence across generations. I think there are a number of important concerns about Artificial General Intelligence, however I'm more concerned about the chance for modified life that can replicate itself autonomously -- either as an entity that starts as "silicon" or starts with a carbon based life form. The speed of improvement of gene editing technology with GenAI is a much more immediate worry to me than AGI. https://lnkd.in/g7JCk5GM What do you think? Chunka Mui Paul Baier Toby Eduardo Redshaw Adam Gutstein

'Much as ChatGPT learns to generate language by analyzing Wikipedia articles, books and chat logs, Profluent’s technology creates new gene editors after analyzing enormous amounts of biological data, including microscopic mechanisms that scientists already use to edit human DNA.' https://lnkd.in/dBtPVaQS

Breaking: AI has successfully edited human DNA. Everything you need to know about OpenCRISPR-1: Profluent has trained an LLM on a massive amount of biological data. The model is able to generate millions of diverse CRISPR-like proteins which don't exist in nature. OpenCRISPR-1 is now the world’s first AI-generated human gene editor. What's more, they're open-sourcing it, making it free to use. Why does this matter? While many are exploring AI applications that go from 1→n, gene editing presents a 0→1 opportunity to fundamentally change the blueprint that makes us human: our DNA. We are one step closer to AI designing exactly what’s needed to create bespoke cures for diseases—this really excites me. If you enjoy insights like this, follow me Alex Banks for more on AI.

This fusion of AI and gene editing technology is incredible! The potential of OpenCRISPR-1 is truly remarkable, especially since it's open-sourced. The potential benefits range from increased efficiency and precision to better custom solutions. I think one day it will even have the potential to assess ethical considerations! This technology will lead to tremendous improvements in gene editing IF used safely and wisely. It's exciting to see AI driving such transformative innovations in our quest to enhance human well-being! Thanks for sharing, Alex Banks! #AI #Genomics #CRISPR