Senior Research Scientist

About The Role

Join our team as a Senior Molecular Biologist where you'll collaborate directly with our Chief Scientific Officer and Director of Biology to drive forward our strategic initiatives. In this role, you'll leverage cutting-edge molecular biology techniques to investigate drug resistance mechanisms, playing a pivotal role in shaping the scientific direction of our company.

Requirements

Key Responsibilities Will Include

• Spearheading innovative CRISPR-based chemogenetic screens to uncover drug response and resistance mechanisms
• Engineering cell lines to express novel proteins and conducting proteomic assays
• Conducting affinity purification assays and overseeing off-site proteomic analysis
• Designing unique in situ reporter assays to evaluate cellular responses to perturbagens
• Collaborating with computational team members to analyze and model experimental data
• Developing and implementing experimental strategies to understand cellular evolution under anti-cancer treatments
• Managing vendors and external contractors to ensure project goals are met
• Presenting research findings at top conferences and in leading journals
  
  
  

Desired Qualifications

• A PhD in genetics, molecular biology, biochemistry, or related field
• Experience with end-to-end CRISPR screening protocols and cell engineering techniques
• Strong background in designing and executing independent research experiments
• Passion for innovative and rigorous scientific inquiry
• Familiarity with protein-protein interaction mapping techniques is a plus
• Previous experience with in vivo animal work and flow cytometry is advantageous
• Ability to work in our New York City lab facilities
  
  
  

Benefits

• Competitive salary range: $110,000 - $140,000
• Equity participation: 0.3% - 0.6%
• Comprehensive health, dental, and vision insurance
• Commuting benefits for New York City employees
• Unlimited PTO days and Paid Family Leave
• Exciting growth opportunities within our fast-paced environment
• Convenient office location in the heart of New York City's biotech community
• Collaborative and enthusiastic team dedicated to solving complex scientific challenges