Vividion Therapeutics, Inc.

Scientist I/II, Immunology

Description

*Note: exact level – Scientist I or Scientist II – depending on experience*

Company Overview

Vividion is a next generation biotechnology company based in San Diego that is leveraging its proprietary chemical proteomics platform to conduct proteome-wide footprinting of drug-protein interactions with unprecedented breadth and precision. Our technology allows us to screen, identify and optimize novel drugs that selectively bind virtually any protein, including proteins previously considered “undruggable”. Our pipeline and emerging programs reflect a matured and productive platform capable of delivering first in class drugs utilizing novel mechanisms of action (allosteric inhibitors, protein-protein interaction inhibitors, functional activators, degraders etc.) against undruggable targets in the oncology and immunology space.

We are uniquely structured with opportunities for all scientists to contribute to both established programs as well as ongoing early target selection, screens and validation. We prize scientific excellence, creativity, team players and we are committed to continued innovation. We have worked hard to create a collaborative and dynamic work culture where your ideas and discoveries are valued and will have an impact. We are growing and there are opportunities for mentorship and career progression.

Vividion was ranked #2 mid-size company on The San Diego Union-Tribune's 2022 and 2023 Top Workplaces list.

Job Summary

The successful candidate will have a strong background in immunology with extensive hands-on experience in molecular and cellular biology, biochemical assay development, and mammalian cell culture techniques, including primary immune cells. This position will be responsible for leading/supporting efforts towards the identification and validation of novel immunology drug targets via multiple mechanisms, including testing the effects of tool compounds on proteins in cellular and biochemical settings, and the use of Vividion’s proprietary chemical proteomics platform.

Requirements

Education and Experience requirements:

  • PhD in immunology or related field with 0-3 years of post-doctoral or industry experience (or both).
  • Expertise in multi-color flow cytometry and isolation of primary human and murine immune cells.
  • Development and optimization of functional immune cell-based in vitro and ex vivo assays.
  • Strong molecular biology skill set: CRISPR, transient transfection, viral transduction, gene expression analysis, protein expression analysis (multiplex cytokine ELISA, Western Blot), qPCR, plasmid design and site-directed mutagenesis.
  • Expertise in human autoimmune diseases is preferred.
  • Industry experience working with small molecules is a plus.

Required Key Attributes

  • Candidates must have strong communication skills and the ability to present results to large teams.
  • Candidates must have effective and independent troubleshooting and problem-solving skills.
  • Candidates must be an effective team player, strong individual contributor, flexible, and able to handle multiple tasks and deliver high quality results in a timely manner.

Pay & Benefits

The annual base salary for this position ranges from $110,000 to $130,000 depending on relevant skills, experience, and education. In addition, this position is eligible for target bonus, long-term-incentives, 401k retirement savings plan with company match, and a comprehensive benefits package which includes medical, dental, vision, life, and disability insurance.

EEO & Employment Eligibility

Vividion Therapeutics, Inc. is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Privacy Policy

The protection of your personal information is a commitment we take seriously. For information regarding our Privacy Policy (CA candidates) please visit https://vividion.com/publication/privacy-noticeforcalifornia-candidates/.
  • Seniority level

    Entry level
  • Employment type

    Full-time
  • Job function

    Research, Analyst, and Information Technology
  • Industries

    Biotechnology Research

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