Hello from Saint-Malo, where we are attending the Association Française d'Histotechnologie Congress. Thank you to Patrice HEMON, PhD, for his presentation on the application of Imaging Mass Cytometry™ in the field of #cancerresearch. He highlighted a study led by Marion Le Rochais at LBAI - B Lymphocytes, Autoimmunity and Immunotherapies - Inserm U1227, which shows how IMC™ can help to define biomarkers of prognostic and therapeutic importance, improve our understanding of cancer progression and its resistance mechanisms to the immune system and develop treatments directed against new therapeutic targets through the use of a 39-marker protein panel in colorectal cancer tissues. #translationalresearch #clinicalresearch David G. Aurélie Bouchareine
Standard BioTools
Biotechnology Research
South San Francisco, California 31,059 followers
Providing essential, standardized tools to accelerate breakthroughs in human health Microfluidics | Cytometry | Imaging
About us
Fluidigm is now Standard BioTools. A company and a name that reflects our commitment to you and your research … To unleash the power of essential, standardized tools that help the life science industry develop breakthrough medicines faster and better. We are evolving to better meet the needs of our customers, bridging a robust and established portfolio of next-generation technologies with an experienced team of leaders dedicated to operational excellence. Standard BioTools – Unleashing reliable tools to accelerate breakthroughs in human health • Providing trusted and repeatable insights that transform scientific discoveries into better outcomes • Improving operating systems through more focused, methodical and consistent processes and an emphasis on quality • Delivering important value to our customers and their research
- Website
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http://www.standardbio.com
External link for Standard BioTools
- Industry
- Biotechnology Research
- Company size
- 501-1,000 employees
- Headquarters
- South San Francisco, California
- Type
- Public Company
- Specialties
- Mass Cytometry, Tissue Imaging, NGS Library Prep, Genotyping, Gene Expression, Copy Number Variation, Real-Time PCR, and Single-Cell Genomics
Locations
Employees at Standard BioTools
Updates
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Exciting cardiovascular research out of the University of Toronto demonstrates that macrophage-engineered human cardiac microtissues represent a considerably improved model for human heart development and reveal a major beneficial role for human primitive macrophages in enhancing early cardiac tissue function. The paper states that multidimensional #CyTOF analysis showed hESC-macrophages can reduce mitochondrial debris, increase ATP production and realign cardiomyocyte metabolism to approximate early fetal ventricular cardiomyocytes. Hamidzada, H. et al. Nature Cardiovascular Research (2024): https://lnkd.in/gtbWY8wd
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We are thrilled to be supporting the Translational Immunology School happening this week in Chiemsee, Germany. New technologies are helping us understand more complex biology, opening doors to applying what we’ve learned to the design of novel therapeutics. Whole slide tissue imaging using protein markers allows the visualization of the overall heterogeneity of a tissue sample, reveals structural variations across the sample and can assist in pinpointing a focus area of activity. Melissa Klug will be presenting this application in tomorrow’s talk: High-plex whole slide spatial biology assays for translational immuno-oncology research. More about the School: https://lnkd.in/gysFNdCV More on #spatialbiology: https://lnkd.in/g8aHFdSF #translationalresearch #immunology
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Regular pathogen surveillance is key all year round as a method to help control outbreaks, with epidemiologically significant variants constantly emerging. qPCR is universally used to detect and quantify pathogens, but conventional methods are time consuming and labor-intensive when several pathogens must be detected in a short period, such as when rapid detection of a virus with multiple mutations is required. Take a look through these examples of how the simultaneous detection and quantification of a large number of pathogens using IFCs instead of microtiter plates can reduce cost, time, labor and reagents: https://lnkd.in/gKjBzxYy #wastewater #respiratoryviruses #foodborneillness #antimicrobialresistance
Rapid pathogen detection for safer communities
standardbio.com
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Thank you to Jolanda Sarno, PhD, Junior Group Leader, Tettamanti Research Center, Fondazione IRCCS San Gerardo dei Tintori, for her excellent talk at the GIC Italian Cytometry Conference this week! She discussed how single-cell classification of B-cell precursor acute lymphoblastic #leukemia by #CyTOF reveals predictors of treatment resistance. We appreciate the interest and questions at the Standard BioTools booth about the ease of analyzing immune cells, intracellular cytokines, intracellular phosphoproteins, transcription factors and cell state simultaneously, and a big thanks to Paolo Santino, Glòria Martrus Zapater, Daniela Natale!
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Don’t miss it! Reserve your seat for this complimentary one-day event, including lunch and evening cocktail and networking reception: https://lnkd.in/gX-qAvSU Celebrate with us, and take the opportunity to talk with leaders in the fields of immunology, biomedicine, pathology and more… as they discuss how single-cell technologies advance our understanding of disease using immune profiling, tissue mapping, functional analysis, biomarker identification and applied data analysis. See you in San Francisco on June 17!
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We are summer ready at #EACR2024! Stop by Booth 59 to meet the team and discuss how immune, protein and genomic profiling approaches can support discovery through screening… And see technology in action at these poster presentations: Tuesday, June 11 | 11:00 am–6:00 pm → Poster 1258: Next Generation of #SpatialBiology: High-Throughput Multiplexed Imaging Mass Cytometry™ With Whole Slide Modes → Poster 1260: Novel Whole Slide #Imaging Modes for Imaging Mass Cytometry Unveil Extensive Cellular Heterogeneity in Human Gliomas Wednesday, June 12 | 11:00 am–6:00 pm → Poster 1257: Enabling Fast and Convenient #ImmuneProfiling of Fresh and Long-Term Stabilized Human Whole Blood Samples With CyTOF® → Poster 1259: Novel Whole Slide Imaging Modes for Imaging Mass Cytometry Reveal Cellular and Structural Composition of Mouse #Glioblastoma
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Complementarity among technologies can expand how we think about research questions. It can broaden our approach and offer more insights from each sample. Hear Jared Burks, PhD, discuss ways in which we can multiplex multiple modalities together. Learn how technologies can work in harmony, pairing suspension and imaging data, to answer larger and more detailed questions. Walk through one of these processes with Burks: https://lnkd.in/gEpEcsNV #multiplexing #cytometry #imaging #innovation
Harmonizing Multiplex Modalities Together with Jared Burks (CYTO 2024)
videos.imaging.standardbio.com
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In a study of mouse embryo normal brain and glioblastoma tissues, a 44-marker neuro-oncology panel composed of the Maxpar OnDemand™ Mouse Immuno-Oncology IMC™ Panel Kit and the Maxpar Neuro Phenotyping IMC Panel Kit revealed the spatial distribution of over 40 distinct molecular markers. A Preview Mode scan using Hyperion XTi™ rapidly identified areas with high tumor and immune cell activity, which was used to identify relevant regions of interest for detailed Cell Mode investigation. Multiplex Cell Mode images using tumor- (top) and immune- (bottom) specific markers demonstrate the heterogeneity of the tumor microenvironment. Get more details on this and other applications for high-plex tissue imaging: https://lnkd.in/gwSDzSaD #lookbook #spatialbiology #neurooncology #tumorcell #immunecell #glioblastoma
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Why not do other things with your day? Hear how the automation built into CyTOF XT™ can change the way you work. Watch this and other thoughts on using CyTOF® technology: https://lnkd.in/gBYfBFzM #cytometry #labautomation
The "amazing" CyTOF® XT
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