Comanche Biopharma

To mark the end of Preeclampsia Awareness Month, we're honored to share a 'Preeclampsia Champions of Change' Q&A interview with Candice Privott, a Patient Advocate with Beth Israel Deaconess Medical Center and a member of Comanche's Patient Advisory Board. Candice developed preeclampsia in her first pregnancy, which ended in the devastating loss of her first son, who was stillborn. Under the care of a Maternal-Fetal Medicine specialist in her subsequent pregnancy, in which she also developed preeclampsia, Candice safely delivered her second son, Grayson. She decided to channel her personal experiences into advocacy. In this Q&A Candice discusses her journey and her work advocating for better education, communication, and care to help ensure that no woman feels unprepared and unsupported during pregnancy. Read the Q&A with Candice here: https://bit.ly/3X3iQdV It's been an honor to hear and share the inspiring stories of several members of our Patient Advisory Board this month. We look forward to sharing additional stories from our Patient Advisors in the coming months. Photo: Candice at the birth of her son Grayson. #preeclampsia #maternalhealth #pregnancy #maternalequity #PatientAdvocate #PreAM24

This week, in our 'Preeclampsia Champions of Change' series we feature a Q&A with Melissa J. Moore, Ph.D., Chief Scientific Officer Emerita, Moderna, and Professor, RNA Therapeutics Institute at UMass Chan Medical School, who is a Scientific Co-Founder of Comanche Biopharma, as well as a member of our Scientific Advisory Board. A preeclampsia survivor herself, Melissa is also a member of Comanche's Patient Advisory Board. In the Q&A, Melissa describes her personal experience with #preeclampsia and how it impacted her both personally and professionally. She shares the serendipitous story behind the discovery and development of an investigational #siRNA therapeutic for preeclampsia and explains why this project has been such a pivotal endeavor for her. Read the Q&A here: https://bit.ly/3x4yLOe #pregnancy #maternalhealth #RNA

On #WorldPreeclampsiaDay, we recognize the pioneering research being conducted by physicians and scientists, including Sarosh Rana, MD, MPH, and her colleagues at The Rana Preeclampsia Laboratory at University of Chicago, to better understand and treat #preeclampsia to improve outcomes for pregnant women and their babies in the US and globally. Read more about the Rana Preeclampsia Laboratory's mission and work here: https://bit.ly/4dSuJZV

Today, as part of our ongoing Preeclampsia Champions of Change series and in honor of #WorldPreeclampsiaDay we feature a Q&A with Kara Boeldt, Founder and Director of Endpreeclampsia.org, a group who seeks to make an impact in education, advocacy, and support. We’re also honored to have Kara serve as a member of Comanche’s Patient Advisory Board. Kara experienced liver failure, kidney failure, and cerebral edema due to severe #preeclampsia at 31 weeks gestation, resulting in the emergent delivery of her daughter. She ultimately transformed this traumatic personal experience with preeclampsia into an opportunity to help others. Kara decided to build a supportive community to help people navigate through this time of often heightened uncertainty and anxiety, giving them a safe place to share their concerns, frustrations, and grief, and to ask questions of trained peer-educators. Today, this community has over 50,000 members in 115 countries. Read more about Kara’s inspiring story: https://bit.ly/3UUX6xY Photo: Kara with her daughter, born at 31 weeks and weighing just 2.5 pounds. #maternalhealth #patientadvocacy #advocacy #pregnancy

Please take a moment to read Monica's heart-wrenching journey with preeclampsia, a condition that I too experienced. Each story, like Monica’s, deepens my commitment to defeat this condition, ensuring that no family has to suffer as we have.

In our ‘Preeclampsia Champions of Change’ Q&A series this month, we’re honored to share the personal experiences of some of our remarkable Patient Advisors. Through these powerful stories, we hope to build awareness of #preeclampsia, including its devastating near- and long-term impact on mothers and their babies, and the need for education and advocacy around this prevalent and serious medical condition in pregnancy. This week, we hear from Monica Juarez, who was diagnosed with preeclampsia when pregnant with her twins. Monica delivered at 22 weeks. Her daughter survived, spending 110 days in the NICU. Tragically, her son did not. Read our full Q&A with Monica: https://bit.ly/44wsJlU Photo: Monica with her daughter Amelia in the NICU about six days after she was born. "I believe this was the first time I was allowed (and summoned the courage) to touch her." - Monica Juarez #PreAM24 #maternalhealth #pregnancy

This May, during #Preeclampsia Awareness Month, we aim to enhance understanding and spread information about this life-threatening complication of pregnancy. The Preeclampsia Foundation, a leader in preeclampsia research and education, offers helpful resources that can empower pregnant women and their loved ones. Learn more: www.preeclampsia.org

May is #Preeclampsia Awareness Month!    Throughout May, we’ll help raise awareness of preeclampsia’s devastating impact and highlight progress toward a future where #pregnancy is safer around the world.   At Comanche, we are so fortunate to have the dedication and passion of our Patient Advisory Board. We are both moved and motivated by the personal stories and conviction of these preeclampsia survivors and maternal health advocates.   Through our ‘Preeclampsia Champions of Change’ series this month, we’ll share the personal experiences of some of these remarkable ambassadors.   Meet all of our Patient Advisors: https://bit.ly/3UbXsRT   #PreAM24 #PredictPreventPrevail #MyPreeclampsiaStory

At Comanche Biopharma, we are honored to have the support and involvement of our Patient Advisory Board, an assembly of remarkable preeclampsia survivors who want to channel their experiences into action and impact for others. As #BlackMaternalHealthWeek wraps up today, we’re sharing some thoughts from our Patient Advisory Board member, Nasia S. (Smith), on how Black women can advocate for themselves during pregnancy: “To my fellow Black women, let us be cognizant of our increased risk of preeclampsia. Together, we have the power to redefine the narrative of black maternal health and ensure equity in every facet of our maternal well-being. As Black women, we grapple with an elevated risk of preeclampsia. Hence, it is of utmost importance to be proactive in seeking regular healthcare. Moreover, let us amplify our voices to disrupt the status quo that persists in healthcare, disproportionately affecting us. Lastly, it is crucial to utilize and engage with resources like BlackMamasMatter.org that advocate for us. Our lives, and those of our future children, deserve more than the current state of maternal health disparities.”   Read about Nasia and all of our Patient Advisory Board members: https://bit.ly/3UbXsRT #BMHW24 #BlackMamasMatter #MaternalEquity #ENDMaternalMortality

Millions of pregnancies are affected by preeclampsia, contributing to the escalating maternal mortality crisis.   During #BlackMaternalHealthWeek, we want to amplify the fact that, while any woman can develop preeclampsia in pregnancy, the risk is significantly higher for Black women.   Several factors may be linked to this shocking disparity, including:   • lack of healthcare access • unconscious bias that can affect healthcare provider decision-making • higher rates of other conditions that are risk factors for developing preeclampsia Our mission at Comanche Biopharma is to develop and make globally available the first treatment targeting a root cause of preeclampsia.   Our purpose is to make every pregnancy around the world safer.   #BMHW24 #BlackMamasMatter #MaternalEquity #ENDMaternalMortality