Great Ormond Street Hospital for Children NHS Foundation Trust

We're delighted to see the impact of this UK first for #epilepsy treatment. ✨ A multi-disciplinary team from GOSH, the University of Oxford, UCL and the Royal Academy of Engineering recently came together to deliver the first UK clinical trial in children of deep brain stimulation for a type of severe epilepsy called Lennox-Gastaut Syndrome. 13-year-old Oran was the first patient to benefit from this clinical trial, which began here at GOSH. Watch his journey in the video below 👇 Surgical, nursing, neurology, imaging, anaesthetics, neurophysiology and many more teams have worked tirelessly to deliver this life-changing research and Innovation for the first patient, led by Martin Tisdall, Consultant Paediatric Neurosurgeon at GOSH and Honorary Associate Professor at UCL. Martin said: “Every single day we see the life-threatening and life-limiting impacts of uncontrollable epilepsy. It can make school, hobbies or even just watching a favourite TV show utterly impossible. “Deep brain stimulation brings us closer than ever before to stopping epileptic seizures for patients who have very limited effective treatment options.” Oran’s seizures started two weeks after his third birthday and up until the trial he hadn’t had a single day without a seizure. He needed round-the-clock care. Oran’s Mum Justine said: “We’ve tried everything, but this is the first real shot we’ve been given in years, there has been no ‘what next’ until now. “Unless somebody takes the first step on a trial like this, there is never going to be a better, and there has to be a better for our family. "We’ve seen a big improvement; seizures have reduced and are less severe. That’s been great but the quality-of-life improvement has been invaluable for Oran. “The team really do have your back. We never felt alone, from last August [when we joined the trial]. We were made to feel part of the team and so was Oran.” “The future looks hopeful which I wouldn’t have dreamed of saying six months ago. For Oran, having hope brings excitement. It makes the future brighter and more attainable even. I’m really pleased that Oran gets to experience that.” #DBS #Epilepsy #Research

Since we opened in 1852, we've always relied on charity support to make GOSH extra special for the children and young people we care for. Great Ormond Street Hospital Charity's wonderful new look and feel means they can help us better than ever, now and in the future 💙

Did you spot Oran and his family on #BBCBreakfast this morning? Oran's the first child in the UK to take part in a clinical trial for a new #epilepsy treatment. 👇

We know that we’re not caring completely for children and young people if we’re not caring for the environment we live in, so when writing our hospital’s five-year strategy, we sought to go above and beyond for the environment. 🌍 In 2021, this strategy led us to become the first London hospital to declare a Climate and Health Emergency, aiming to become a net zero carbon organisation by 2040. ♻️ Three years later, in honour of #CleanAirDay, we’ve met with Professor Pia Hardelid a Professor of Epidemiology at UCL GOS ICH, to discuss her current project: ‘The Kids’ Environment and Health Cohort.’ Prof Hardelid’s seeking to link data from organisations like hospitals and schools, to help us better understand the impacts of local environments on children’s health, employing data from over 10 million children born in England since 2006. “This means that it will be possible to study how, for example, climate change will impact children with rare or complex conditions, and what we can do to support their health in a changing environment, via better services, support or planning.” - Professor Hardelid Learn more about the project: https://lnkd.in/ehZ7qwTT

This week we had the pleasure of hosting colleagues from across Europe for an exciting two days of discussions on the #PHEMS project 🙌 PHEMS is a trail-blazing project made up of six leading, digitally advanced children’s hospitals in Europe and aims to improve the way that we use healthcare data to accelerate research, further our understanding of conditions and ultimately improve outcomes for patients. 🚀 As well as being a brilliant opportunity to get to know each other better, the visit which took place at our GOSH DRIVE Unit, allowed us to have collaborative interactive discussions and to look ahead to the future! 🤝 We are delighted to be working alongside such brilliant hospitals and partners to jointly lead the way in this field! 🌟 Read more about the PHEMS Project: https://lnkd.in/eZMrN2rq HUS Helsingin yliopistollinen sairaala Erasmus Universiteit Rotterdam Azienda Ospedaliera Universitaria Meyer - IRCCS Hospital Sant Joan de Déu Barcelona Bērnu klīniskā universitātes slimnīca Tietoevry VEIL.AI Aridhia – Digital Research Environment – DRE The Hyve GENESIS Biomed

Happy #PrideMonth everyone! 💙 Huge thanks to everyone who gave their time to share their best wishes 👇 👏

Did you see Ada on BBC News Breakfast this morning? Together with her Mum Rachelle, they've been sharing this week's incredible #research news. Researchers have discovered a genetic therapy that could be used to reverse large and painful giant moles caused by congenital melanocytic naevus syndrome (CMN). For children with CMN, up to 80% of their body can be covered in large, painful, or itchy moles that can develop into melanoma. This new therapy, developed by researchers from GOSH, UCL Great Ormond Street Institute for Child Health, and The Francis Crick Institute, could reverse these giant moles after further studies. Three-year-old Ada has 70% of her body covered in CMN. She loves swimming and the sea but needs extra precautions to protect her skin. This research was made possible by the hundreds of GOSH patients who supported the study. Ada's parents, Rachelle and Greg, donated Ada's skin cells for Dr. Veronica Kinsler’s research. Rachelle shared: “When we heard about this research project, we wanted to do everything we could to try and help Dr Kinsler and her team." "We never stop thinking and worrying what life will be like for Ada as she grows and becomes more aware of her CMN and, how it will affect her long term. “Knowing there has been a huge step forward in the CMN research and there could be a chance of Ada’s CMN being reversed and possibly reducing Ada’s risk of developing melanoma, has blown our expectations out of the water. “It is mind-blowing to think that this treatment option could be available in only a matter of years.” Now at nursery, Ada enjoys being creative and loves arts and crafts and playing role play with her older siblings. Read more about this research breakthrough and the incredible impact it could have for children like Ada: https://lnkd.in/eb5EQbvk #GeneTherapy #ResearchBreakthrough Caring Matters Now LifeArc

Want to understand how the #NHS and local authorities can help raise awareness around air pollution and improve our air? Join experts and advocates at the Cleaner Air, Healthier Lives Summit on Thursday 20 June 2024, #CleanAirDay. Organised by GOSH, London Borough of Camden and Global Action Plan, this event will bring together those working in the health sector and on health in local authorities to explore the importance of clean air for long-term health and the steps needed to create healthier environments for all. The Cleaner Air, Healthier Lives Summit will demonstrate how considering cleaner air as a preventative medicine will align the NHS and local authorities in stepping up efforts to improve air quality, reducing exposure for people in the most vulnerable circumstances, and building healthier and more resilient communities. Register for your free place today: https://lnkd.in/eNSrZbCb

We know Father's Day can be a difficult time for our GOSH families and staff. 🌻 We're sending love to fathers with seriously ill children, those who have lost their child or their father, and carers, foster dads and grandfathers, too. Know you are not alone 💙

Lovely to welcome Josie from This Morning 💙 Joining young patients and their families on Elephant Ward, Josie heard all about creative syringe painting in the playroom, special teddies and collecting beads of courage with our nurses – just a few ways we support children during their cancer treatment. Josie also met with our staff to discuss the difference our new Children’s Cancer Centre will make, with better and bigger spaces to help aid our patients’ recovery.