It’s a bird! It’s a plane! It’s a…dragon? A SpaceX Dragon spacecraft is set to launch into orbit atop the Falcon 9 rocket toward the International Space Station for its 12th commercial resupply (CRS-12) mission August 14 from our Kennedy Space Center in Florida.

It won’t breathe fire, but it will carry science that studies cosmic rays, protein crystal growth, bioengineered lung tissue.

Here are some highlights of research that will be delivered:

I scream, you scream, we all scream for ISS-CREAM! 

Cosmic Rays, Energetics and Mass, that is! Cosmic rays reach Earth from far outside the solar system with energies well beyond what man-made accelerators can achieve. The Cosmic Ray Energetics and Mass (ISS-CREAM) instrument measures the charges of cosmic rays ranging from hydrogen to iron nuclei. Cosmic rays are pieces of atoms that move through space at nearly the speed of light

The data collected from the instrument will help address fundamental science questions such as:

• Do supernovae supply the bulk of cosmic rays?
• What is the history of cosmic rays in the galaxy?
• Can the energy spectra of cosmic rays result from a single mechanism?

ISS-CREAM’s three-year mission will help the scientific community to build a stronger understanding of the fundamental structure of the universe.

Space-grown crystals aid in understanding of Parkinson’s disease

The microgravity environment of the space station allows protein crystals to grow larger and in more perfect shapes than earth-grown crystals, allowing them to be better analyzed on Earth. 

Developed by the Michael J. Fox Foundation, Anatrace and Com-Pac International, the Crystallization of Leucine-rich repeat kinase 2 (LRRK2) under Microgravity Conditions (CASIS PCG 7) investigation will utilize the orbiting laboratory’s microgravity environment to grow larger versions of this important protein, implicated in Parkinson’s disease.

Defining the exact shape and morphology of LRRK2 would help scientists to better understand the pathology of Parkinson’s and could aid in the development of therapies against this target.

Mice Help Us Keep an Eye on Long-term Health Impacts of Spaceflight

Our eyes have a whole network of blood vessels, like the ones in the image below, in the retina—the back part of the eye that transforms light into information for your brain. We are sending mice to the space station (RR-9) to study how the fluids that move through these vessels shift their flow in microgravity, which can lead to impaired vision in astronauts.

By looking at how spaceflight affects not only the eyes, but other parts of the body such as joints, like hips and knees, in mice over a short period of time, we can develop countermeasures to protect astronauts over longer periods of space exploration, and help humans with visual impairments or arthritis on Earth.

Telescope-hosting nanosatellite tests new concept

The Kestrel Eye (NanoRacks-KE IIM) investigation is a microsatellite carrying an optical imaging system payload, including an off-the-shelf telescope. This investigation validates the concept of using microsatellites in low-Earth orbit to support critical operations, such as providing lower-cost Earth imagery in time-sensitive situations, such as tracking severe weather and detecting natural disasters.

Sponsored by the ISS National Laboratory, the overall mission goal for this investigation is to demonstrate that small satellites are viable platforms for providing critical path support to operations and hosting advanced payloads.

Growth of lung tissue in space could provide information about diseases

The Effect of Microgravity on Stem Cell Mediated Recellularization (Lung Tissue) uses the microgravity environment of space to test strategies for growing new lung tissue. The cells are grown in a specialized framework that supplies them with critical growth factors so that scientists can observe how gravity affects growth and specialization as cells become new lung tissue.

The goal of this investigation is to produce bioengineered human lung tissue that can be used as a predictive model of human responses allowing for the study of lung development, lung physiology or disease pathology.

These crazy-cool investigations and others launching aboard the next SpaceX #Dragon cargo spacecraft on August 14. They will join many other investigations currently happening aboard the space station. Follow @ISS_Research on Twitter for more information about the science happening on 250 miles above Earth on the space station.  

Watch the launch live HERE starting at 12:20 p.m. EDT on Monday, Aug. 14!

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A growing number of commercial partners use the International Space Station National Lab. With that growth, we will see more discoveries in fundamental and applied research that could improve life on the ground.

Space Station astronaut Kate Rubins was the first person to sequence DNA in microgravity.

Since 2011, when we engaged the Center for the Advancement of Science in Space (CASIS) to manage the International Space Station (ISS) National Lab, CASIS has partnered with academic researchers, other government organizations, startups and major commercial companies to take advantage of the unique microgravity lab. Today, more than 50 percent of CASIS’ experiments on the station represent commercial research.

Here’s a look at five ways the ISS National Lab is enabling new opportunities for commercial research in space.

1. Supporting Commercial Life Sciences Research

One of the main areas of focus for us in the early origins of the space station program was life sciences, and it is still a major priority today. Studying the effects of microgravity on astronauts provides insight into human physiology, and how it evolves or erodes in space. CASIS took this knowledge and began robust outreach to the pharmaceutical community, which could now take advantage of the microgravity environment on the ISS National Lab to develop and enhance therapies for patients on Earth. Companies such as Merck, Eli Lilly & Company, and Novartis have sent several experiments to the station, including investigations aimed at studying diseases such as osteoporosis, and examining ways to enhance drug tablets for increased potency to help patients on Earth. These companies are trailblazers for many other life science companies that are looking at how the ISS National Lab can advance their research efforts.

2. Enabling Commercial Investigations in Material and Physical Sciences

Over the past few years, CASIS and the ISS National Lab also have seen a major push toward material and physical sciences research by companies interested in enhancing their products for consumers. Examples range from Proctor and Gamble’s investigation aimed at increasing the longevity of daily household products, to Milliken’s flame-retardant textile investigation to improve protective clothing for individuals in harm’s way, and companies looking to enhance materials for household appliances. Additionally, CASIS has been working with a variety of companies to improve remote sensing capabilities in order to better monitor our oceans, predict harmful algal blooms, and ultimately, to better understand our planet from a vantage point roughly 250 miles above Earth.

3. Supporting Startup Companies Interested in Microgravity Research 

CASIS has funded a variety of investigations with small startup companies (in particular through seed funding and grant funding from partnerships and funded solicitations) to leverage the ISS National Lab for both research and test-validation model experiments. CASIS and The Boeing Company recently partnered with MassChallenge, the largest startup accelerator in the world, to fund three startup companies to conduct microgravity research.

4. Enabling Validation of Low-Earth Orbit Business Models 

The ISS National Lab helps validate low-Earth orbit business models. Companies such as NanoRacks, Space Tango, Made In Space, Techshot, and Controlled Dynamics either have been funded by CASIS or have sent instruments to the ISS National Lab that the research community can use, and that open new channels for inquiry. This has allowed the companies that operate these facilities to validate their business models, while also building for the future beyond station.

5. Demonstrating the Commercial Value of Space-based Research

We have been a key partner in working with CASIS to demonstrate to American businesses the value of conducting research in space. Through outreach events such as our Destination Station, where representatives from the International Space Station Program Science Office and CASIS select cities with several major companies and meet with the companies to discuss how they could benefit from space-based research. Over the past few years, this outreach has proven to be a terrific example of building awareness on the benefits of microgravity research.

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As a child, Kate Rubins dreamed of being an astronaut and a scientist. During the past four months aboard the International Space Station, that dream came full circle. She became the first person to sequence DNA in space, among other research during her recent mission, adding to her already impressive experience. She holds a doctorate in molecular biology, and previously led a lab of 14 researchers studying viruses, including Ebola.

Here’s a look back at Rubins in her element, conducting research aboard your orbiting laboratory.

Kate inside Destiny, the U.S. Laboratory Module

The U.S. national laboratory, called Destiny, is the primary research laboratory for U.S. payloads, supporting a wide range of experiments and studies contributing to health, safety, and quality of life for people all over the world. 

Destiny houses the Microgravity Science Glovebox (MSG), in which Kate worked on the Heart Cells experiment.

Swabbing for Surface Samples

Microbes that can cause illness could present problems for current and future long duration space missions. 

Understanding what microbe communities thrive in space habitats could help researchers design antimicrobial technology. Here, Kate is sampling various surfaces of the Kibo module for the Microbe-IV investigation.

Culturing Beating Heart Cells in Space

The Heart Cells investigation uses human skin cells that are induced to become stem cells, which can then differentiate into any type of cell. 

Researchers forced the stem cells to grow into human heart cells, which Rubins cultured aboard the space station for one month.

Rubins described seeing the heart cells beat for the first time as “pretty amazing. First of all, there’s a few things that have made me gasp out loud up on board the [space] station. Seeing the planet was one of them, but I gotta say, getting these cells in focus and watching heart cells actually beat has been another pretty big one.”

Innovative Applied Research Experiment from Eli Lilly

The Hard to Wet Surfaces investigation from Eli Lilly, and sponsored by the Center for the Advancement of Science in Space (CASIS), looks at liquid-solid interactions and how certain pharmaceuticals dissolve, which may lead to more potent and effective medicines in space and on Earth. 

Rubins set up vials into which she injected buffer solutions and then set up photography to track how tablets dissolved in the solution in microgravity.

Capturing Dragon

Rubins assisted in the capture of the SpaceX Dragon cargo spacecraft in July. The ninth SpaceX resupply mission delivered more than two thousand pounds of science to the space station. 

Biological samples and additional research were returned on the Dragon spacecraft more than a month later.  

Sliding Science Outside the Station

Science doesn’t just happen inside the space station. External Earth and space science hardware platforms are located at various places along the outside of the orbiting laboratory. 

The Japanese Experiment Module airlock can be used to access the JEM Exposed Facility. Rubins installed the JEM ORU Transfer Interface (JOTI) on the JEM airlock sliding table used to install investigations on the exterior of the orbiting laboratory.

Installing Optical Diagnostic Instrument in the MSG

Rubins installed an optical diagnostic instrument in the Microgravity Science Glovebox (MSG) as part of the Selective Optical Diagnostics Instrument (SODI-DCMIX) investigation. Molecules in fluids and gases constantly move and collide. 

When temperature differences cause that movement, called the Soret effect, scientists can track it by measuring changes in the temperature and movement of mass in the absence of gravity. Because the Soret effect occurs in underground oil reservoirs, the results of this investigation could help us better understand such reservoirs.

The Sequencing of DNA in Space

When Rubins’ expedition began, DNA had never been sequenced in space. Within just a few weeks, she and the Biomolecule Sequencer team had sequenced their one billionth “base” – the unit of DNA - aboard the orbiting laboratory. 

The Biomolecule Sequencer investigation seeks to demonstrate that DNA sequencing in microgravity is possible, and adds to the suite of genomics capabilities aboard the space station.

Studying Fluidic Dynamics with SPHERES

The SPHERES-Slosh investigation examines the way liquids move inside containers in a microgravity environment. The phenomena and mechanics associated with such liquid movement are still not well understood and are very different than our common experiences with a cup of coffee on Earth.

Rockets deliver satellites to space using liquid fuels as a power source, and this investigation plans to improve our understanding of how propellants within rockets behave in order to increase the safety and efficiency of future vehicle designs. Rubins conducted a series of SPHERES-Slosh runs during her mission.

Retrieving Science Samples for Their Return to Earth

Precious science samples like blood, urine and saliva are collected from crew members throughout their missions aboard the orbiting laboratory. 

They are stored in the Minus Eighty-Degree Laboratory Freezer for ISS (MELFI) until they are ready to return to Earth aboard a Soyuz or SpaceX Dragon vehicle.

Measuring Gene Expression of Biological Specimens in Space

Our WetLab-2 hardware system is bringing to the space station the technology to measure gene expression of biological specimens in space, and to transmit the results to researchers on Earth at the speed of light. 

Rubins ran several WetLab-2 RNA SmartCycler sessions during her mission.

Studying the First Expandable Habitat Module on the Space Station

The Bigelow Expandable Activity Module (BEAM) is the first expandable habitat to be installed on the space station. It was expanded on May 28, 2016. 

Expandable habitats are designed to take up less room on a spacecraft, but provide greater volume for living and working in space once expanded. Rubins conducted several evaluations inside BEAM, including air and surface sampling.

Better Breathing in Space and Back on Earth

Airway Monitoring, an investigation from ESA (the European Space Agency), uses the U.S. airlock as a hypobaric facility for performing science. Utilizing the U.S. airlock allows unique opportunities for the study of gravity, ambient pressure interactions, and their effect on the human body. 

This investigation studies the occurrence and indicators of airway inflammation in crew members, using ultra-sensitive gas analyzers to evaluate exhaled air. This could not only help in spaceflight diagnostics, but that also hold applications on earth within diagnostics of similar conditions, for example monitoring of asthma.

Hot Science with Cool Flames

Fire behaves differently in space, where buoyant forces are removed. Studying combustion in microgravity can increase scientists’ fundamental understanding of the process, which could lead to improvement of fire detection and suppression systems in space and on Earth. 

Many combustion experiments are performed in the Combustion Integration Rack (CIR) aboard the space station. Rubins replaced two Multi-user Droplet Combustion Apparatus (MDCA) Igniter Tips as part of the CIR igniter replacement operations.

Though Rubins is back on Earth, science aboard the space station continues, and innovative investigations that seek to benefit humans on Earth and further our exploration of the solar system are ongoing. Follow @ISS_Research to keep up with the science happening aboard your orbiting laboratory.  

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Northrop Grumman launched its Cygnus spacecraft into orbit to the International Space Station at 4:01 a.m. EST on Nov. 17 from Wallops Flight Facility in Virginia. Cygnus launched on an Antares rocket carrying crew supplies, equipment and scientific research to crewmembers aboard the station. The spacecraft is named after NASA astronaut and U.S. Navy officer John Young, who walked on the Moon during Apollo 16 and commanded the first space shuttle mission. Throughout his lifetime, Young logged 835 hours in space over the course of six missions.

Antares launched the S.S. John Young from the Mid-Atlantic Regional Spaceport’s Pad-0A on Wallops Island, carrying tons of cargo, including scientific investigations that will study 3D printing and recycling, cement solidification, and crystals that may fight Parkinson’s disease.

Here’s a look at six science-y experiments and research this mission will deliver to the space station.

1. 3D printing and recycling

Refabricator demonstrates an integrated 3D printer and recycler for the first time aboard the space station.

It recycles waste plastic materials into high-quality 3D-printer filament, which could enable sustainable fabrication, repair, and recycling on long-duration space missions.

2. Sensory input in microgravity

Changes in sensory input in microgravity may be misinterpreted and cause a person to make errors in estimation of velocity, distance or orientation.

VECTION, a Canadian Space Agency (CSA) investigation, examines this effect as well as whether people adapt to altered sensory input on long-duration missions and how that adaptation changes upon return to Earth.

3. Solidifying cement in space

The MVP-Cell 05 investigation uses a centrifuge to provide a variable gravity environment to study the complex process of cement solidification, a step toward eventually making and using concrete on extraterrestrial bodies.

4. From stardust to solar systems

Much of the universe was created when dust from star-based processes clumped into intermediate-sized particles and eventually became planets, moons and other objects. Many questions remain as to just how this worked, though.

The EXCISS investigation seeks answers by simulating the high-energy, low gravity conditions that were present during formation of the early solar system. Scientists plan to zap a specially formulated dust with an electrical current, then study the shape and texture of pellets formed.

5. Growing crystals to fight Parkinson’s disease

The CASIS PCG-16 investigation grows large crystals of an important protein, Leucine-rich repeat kinase 2, or LRRK2, in microgravity for analysis back on Earth.

This protein is implicated in development of Parkinson’s disease, and defining its shape and morphology may help scientists better understand the pathology of the disease and develop therapies to treat it. Crystals of LRRK2 grown in gravity are too small and too compact to study, making microgravity an essential part of this research.

6. Better gas separation membranes

Membranes represent one of the most energy-efficient and cost-effective technologies for separating and removing carbon dioxide from waste gases, thereby reducing greenhouse gas emissions. CEMSICA tests membranes made from particles of calcium-silicate (C-S) with pores 100 nanometers or smaller. Producing these membranes in microgravity may resolve some of the challenges of their manufacture on Earth and lead to development of lower-cost, more durable membranes that use less energy. The technology ultimately may help reduce the harmful effects of CO2 emissions on the planet.

For daily updates, follow @ISS_Research.

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SpaceX is scheduled to launch its Dragon spacecraft PACKED with super cool research and technology to the International Space Station June 1 from Kennedy Space Center in Florida. New solar panels, investigations that study neutron stars and even fruit flies are on the cargo list. Let’s take a look at what other bits of science are making their way to the orbiting laboratory 250 miles above the Earth…

New solar panels to test concept for more efficient power source

Solar panels generate power well, but they can be delicate and large when used to power a spacecraft or satellites. This technology demonstration is a solar panel concept that is lighter and stores more compactly for launch than the solar panels currently in use. 

Roll-Out Solar Array (ROSA) has solar cells on a flexible blanket and a framework that rolls out like a tape measure and snap into place, and could be used to power future space vehicles.  

Investigation to Study Composition of Neutron Stars

Neutron stars, the glowing cinders left behind when massive stars explode as supernovas, contain exotic states of matter that are impossible to replicate in any lab. NICER studies the makeup of these stars, and could provide new insight into their nature and super weird behavior.

Neutron stars emit X-ray radiation, enabling the NICER technology to observe and record information about its structure, dynamics and energetics. 

Experiment to Study Effect of New Drug on Bone Loss

When people and animals spend lots of space, they experience bone density loss. In-flight exercise can prevent it from getting worse, but there isn’t a therapy on Earth or in space that can restore bone that is already lost.

The Systemic Therapy of NELL-1 for osteoporosis (Rodent Research-5) investigation tests a new drug that can both rebuild bone and block further bone loss, improving health for crew members.

Research to Understand Cardiovascular Changes

Exposure to reduced gravity environments can result in cardiovascular changes such as fluid shifts, changes in total blood volume, heartbeat and heart rhythm irregularities, and diminished aerobic capacity.

The Fruit Fly Lab-02 study will use the fruit fly (Drosophila melanogaster) to better understand the underlying mechanisms responsible for the adverse effects of prolonged exposure to microgravity on the heart. Fruit flies are effective model organisms, and we don’t mean on the fashion runway. Want to see how 1,000 bottles of fruit flies were prepared to go to space? Check THIS out.

Space Life-Support Investigation

Currently, the life-support systems aboard the space station require special equipment to separate liquids and gases. This technology utilizes rotating and moving parts that, if broken or otherwise compromised, could cause contamination aboard the station. 

The Capillary Structures investigation studies a new method of water recycling and carbon dioxide removal using structures designed in specific shapes to manage fluid and gas mixtures. 

Earth-Observation Tools

Orbiting approximately 250 miles above the Earth’s surface, the space station provides pretty amazing views of the Earth. The Multiple User System for Earth Sensing (MUSES) facility hosts Earth-viewing instruments such as high-resolution digital cameras, hyperspectral imagers, and provides precision pointing and other accommodations.

This investigation can produce data that could be used for maritime domain awareness, agricultural awareness, food security, disaster response, air quality, oil and gas exploration and fire detection. 

Watch the launch live HERE! For all things space station science, follow @ISS_Research on Twitter.

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Later this month, a SpaceX Falcon Heavy rocket will take to the skies for the third time to launch the Department of Defense’s Space Test Program-2 (STP-2) mission. Several exciting, one-of-a-kind NASA technology and science payloads are among the two-dozen spacecraft aboard.

First, let’s talk about that Falcon Heavy rocket. Its 27 engines generate thrust at liftoff equal to that of approximately 18 airplanes, and it can lift over 140,000 pounds.

Managed by the U.S. Air Force Space and Missile Systems Center, STP-2 is the first government-contracted Falcon Heavy launch. It will reuse the two side boosters recovered after the April flight. SpaceX describes it as one of the most challenging launches in the company’s history.

It’s a big deal to us at NASA because we’re launching some pretty cool technologies. The tech will support our future exploration plans by helping improve future spacecraft design and performance. Here’s a bit about each:

Deep Space Atomic Clock

Time is the heartbeat of space navigation. Today, we navigate in deep space by using giant antennas on Earth to send signals to spacecraft, which then send those signals back to Earth. Atomic clocks on Earth measure the time it takes a signal to make this two-way journey. Only then can human navigators on Earth use large antennas to tell the spacecraft where it is and where to go.

Our Jet Propulsion Laboratory has been perfecting an atomic clock fit for exploration missions. The Deep Space Atomic Clock is the first atomic clock designed to fly on a spacecraft destined for beyond Earth’s orbit. The timepiece is lighter and smaller—no larger than a toaster oven—than its refrigerator-sized, Earthly counterparts.

This miniaturized clock could enable one-way navigation: a spacecraft receives a signal from Earth and can determine its location immediately using its own, built-in navigation system. Even smaller versions of the clock are being investigated right now that could be used for the growing number of small to mid-size satellites. As we go forward to the Moon with the Artemis program, precise measurements of time are key to mission success.

The Deep Space Atomic Clock is the primary payload onboard the General Atomics Electromagnetic Systems Orbital Test Bed satellite and will perform a year-long demonstration in space.

Enhanced Tandem Beacon Experiment (E-TBEx)

Two tiny satellites will study how signals can be muddled as they travel through hard-to-predict bubbles in the upper atmosphere. Signals sent from satellites down to Earth (and vice versa) can be disrupted by structured bubbles that sometimes form in Earth’s upper atmosphere. Because this region is affected both by weather on Earth and conditions in space, it’s hard to predict just when these bubbles will form or how they’ll mess with signals.

The E-TBEx CubeSats (short for Enhanced Tandem Beacon Experiment) will try to shed some light on that question. As these little satellites fly around Earth, they’ll send radio signals (like the ones used by GPS) to receiving stations on the ground. Scientists will be able to look at the signals received and see if they were jumbled as they traveled through the upper atmosphere down to Earth — which will help us track when these bubbles are forming and how much they’re interfering with our signals.

Green Propellant Infusion Mission (GPIM)

For decades, we have relied on a highly toxic spacecraft fuel called hydrazine. The Green Propellant Infusion Mission (GPIM) will lay the foundation to replace conventional chemical propulsion systems with a safer and more efficient alternative for next-generation spacecraft.

GPIM will demonstrate a new propellant in space for the first time. Concocted by the U.S. Air Force Research Laboratory, this innovative, “green” fuel—which actually has more of a peach hue—is expected to improve overall spacecraft performance due to its higher density, increased thrust and lower freezing point in comparison with hydrazine.

GPIM’s propulsion system, developed by Aerojet Rocketdyne, consists of new compatible tanks, valves and thrusters. During the two-month-long demonstration on a Ball Aerospace spacecraft, engineers will conduct orbital maneuvers to demonstrate the performance of the propellant and propulsion system.

Space Environment Testbeds (SET)

It’s not easy being a spacecraft; invisible, energetic particles zip throughout space — and while there are so few that space is considered a vacuum, what’s there still packs a punch. Tiny particles — like those seen here impacting a detector on a Sun-studying spacecraft — can wreak havoc with the electronics we send up into space.

Space Environment Testbeds — or SET, for short — is a mission to study space radiation and how it affects spacecraft and electronics in orbit. What looks like snow flurries in these animated images, for example, is actually a solar radiation storm of incredibly fast particles, unleashed by a solar eruption. Energetic particles from the Sun or deep space can spark memory damage or computer upsets on spacecraft, and over time, degrade hardware.

By studying radiation effects and different methods to protect satellites, SET will help future missions improve spacecraft design, engineering and operations.

Follow @NASA_Technology and @NASASun on Twitter for news about the STP-2 launch and our missions aboard.

Check out www.nasa.gov/spacex to stay up-to-date on the launch day and time. Don’t forget to tune into our launch coverage, scheduled to start about 30 minutes before liftoff!

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ALT

The Summer Solstice Is Here!

Today — June 20, 2024 — is the northern summer solstice. In the Northern Hemisphere, it marks the longest day of the year and the official start to summer.

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