CNBC Disruptor 50

These are the 2024 CNBC Disruptor 50 companies: See the full list of startups riding the AI wave

It's fair to say that AI is all over the 12th annual CNBC Disruptor 50 list. 

Roughly two-thirds of the 50 companies making the Disruptor 50 list describe artificial intelligence as "critical" to their businesses. And it starts at the very top: for the first time ever, a company repeats as the list 's No. 1: OpenAI.

AI's remaking of the market extends much further. Thirteen of the 2024 Disruptors call themselves "generative AI companies," including five of the top 10 on this year's list, a group that in all raised at least $5.5 billion from investors in the past year.

Companies in industries ranging from cybersecurity to agriculture are also defining AI as mission critical. And in an important shift from the past Silicon Valley-led disruptive innovation era, the "better, faster, cheaper" mantra funded almost wholly by VCs is on the way out.

AI requires massive capital investment, inevitably leading to close partnership with the incumbent giants rather than just disruptive competition.

In all, the 2024 Disruptors have raised $70 billion at a total implied valuation of $436 billion.

1OpenAIThe first-ever back-to-back top disruptor
2Anduril IndustriesA future fighting force
3Stripe$1 trillion in online transactions
4BrexWell spent
5DatabricksBuilding, bit by bit
6CanvaDesign star
7AnthropicAn Amazon-backed OpenAI threat
8ElevateBioA basecamp for drug discovery
9WizA hyper cyber grower
10ExotecWhat's up in the warehouse
11Octopus EnergyA highly intelligent grid
12Scale AIAI's personal trainer
13NotionCreative collaboration
14FlutterwaveFintech for fast-growing populations
15Relativity SpaceRocket stars
16MonzoOne of Britain's biggest banks
17TranscarentA friend with benefits
18Arctic WolfCold cyber comfort
19EinrideTrucking's next stop
20Thrive MarketAn online grocer to check out
21ZiplineDelivering on drones' promise
22ChimeBanking on more banking distrust
23GrubMarketDigital transformation for America's food supply chain
24Carbon RoboticsThe laser-based weed killer
25Generate:BiomedicinesDesigner AI drugs
26FigmaAdobe's ex, moving on, creating new relationships
27KapitalThe bank that wants small business
28DeelOn a payroll
29Alto PharmacyBig online pharma
30CohereThe gen AI inside more company firewalls
31ZumMaking the yellow school bus green
32RampThe corporate expense hawk
33DedroneSmart air security
34Lead BankAn extreme bank makeover
35PhononicHeating up, and cooling down
36SolugenA sugar fix for the climate
37TalaDeveloping credit in developing markets
38NavanThe corporate traveler
39BeewiseBusy with bee collapse
40AlphaSenseWall Street's AI search engine
41Trust & WillWhere there's a will, there's need for better estate planning
42Gecko RoboticsCritical mission robots
43GleanA Google and a ChatGPT for the enterprise
44DiscordIts game is still on
45Spring HealthCompletely mental
46LineageThe largest link in the global food supply chain
47Abnormal SecurityLooking for phishy business
48WatershedThe operating system for corporate climate commitments
49Maven ClinicWhole-person healthcare for women and families.
50CityblockA high stakes bet on lowering the cost of Medicaid