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A role for frequenin, a Ca2+-binding protein, as a regulator of Kv4 K+-currents.
Nakamura TY, Pountney DJ, Ozaita A, Nandi S, Ueda S, Rudy B, Coetzee WA. Nakamura TY, et al. Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12808-13. doi: 10.1073/pnas.221168498. Epub 2001 Oct 16. Proc Natl Acad Sci U S A. 2001. PMID: 11606724 Free PMC article.
Here, we provide direct evidence that frequenin is a potent and specific modulator of Kv4 channels, the principal molecular components of subthreshold activating A-type K(+) currents. Frequenin increases Kv4.2 current amplitudes (partly by enhancing surface expression of K …
Here, we provide direct evidence that frequenin is a potent and specific modulator of Kv4 channels, the principal molecular components of su …
A Machine Learning Approach for Rate Constants. III. Application to the Cl(2P) + CH4 → CH3 + HCl Reaction.
Houston PL, Nandi A, Bowman JM. Houston PL, et al. J Phys Chem A. 2022 Aug 25;126(33):5672-5679. doi: 10.1021/acs.jpca.2c04376. Epub 2022 Aug 12. J Phys Chem A. 2022. PMID: 35960874
The recrossing effects, which are not described by TST and even sophisticated tunneling corrections, do appear in experiment at temperatures above around 600 K. The ML results describe these effects and in fact merge at 600 K with RPMD results (which can describe re …
The recrossing effects, which are not described by TST and even sophisticated tunneling corrections, do appear in experiment at temperatures …
Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix.
Bellone S, Jeong K, Halle MK, Krakstad C, McNamara B, Greenman M, Mutlu L, Demirkiran C, Hartwich TMP, Yang-Hartwich Y, Zipponi M, Buza N, Hui P, Raspagliesi F, Lopez S, Paolini B, Milione M, Perrone E, Scambia G, Altwerger G, Ravaggi A, Bignotti E, Huang GS, Andikyan V, Clark M, Ratner E, Azodi M, Schwartz PE, Quick CM, Angioli R, Terranova C, Zaidi S, Nandi S, Alexandrov LB, Siegel ER, Choi J, Schlessinger J, Santin AD. Bellone S, et al. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2321898121. doi: 10.1073/pnas.2321898121. Epub 2024 Apr 16. Proc Natl Acad Sci U S A. 2024. PMID: 38625939
Human papillomavirus DNA was detected in 65.6% (42/64) of the tumors. Recurrent mutations were identified in PIK3CA, KMT2D/MLL2, K-RAS, ARID1A, NOTCH2, and RPL10. The top mutated genes included RB1, ARID1A, PTEN, KMT2D/MLL2, and WDFY3, a gene not yet implicated in NETc. .. …
Human papillomavirus DNA was detected in 65.6% (42/64) of the tumors. Recurrent mutations were identified in PIK3CA, KMT2D/MLL2, K-RA …
Low temperature Raman study of a liquid crystalline system 4-decyloxy benzoic acid (4DBA).
Vikram K, Nandi R, Singh RK. Vikram K, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2013 Aug;112:377-83. doi: 10.1016/j.saa.2013.03.009. Epub 2013 Mar 14. Spectrochim Acta A Mol Biomol Spectrosc. 2013. PMID: 23686092
The Raman spectra of a liquid crystalline system, 4-Decyloxy benzoic acid (4DBA) have been recorded at different temperatures within the interval 300-78 K in order to identify the structural changes in crystalline state of a nematogen and to understand the molecular alignm …
The Raman spectra of a liquid crystalline system, 4-Decyloxy benzoic acid (4DBA) have been recorded at different temperatures within the int …
Polyamines are inhibitors of gastric acid secretion.
Ray TK, Nandi J, Pidhorodeckyj N, Meng-Ai Z. Ray TK, et al. Proc Natl Acad Sci U S A. 1982 Mar;79(5):1448-52. doi: 10.1073/pnas.79.5.1448. Proc Natl Acad Sci U S A. 1982. PMID: 6951188 Free PMC article.
Unlike the H2 receptor antagonists, the polyamines are completely ineffective from the nutrient side and are effective only from the secretory side of the chambered mucosa. The polyamine effects could be reversed by increasing K+ concentration in the secretory solution. St …
Unlike the H2 receptor antagonists, the polyamines are completely ineffective from the nutrient side and are effective only from the secreto …